Entrepreneur First companies

Human orchestration for business outcomes.

The AI workspace for financial compliance.

AI infrastructure for inheritance.

America's carbon fiber foundry for unmanned systems.

The annotation stack for robotics and physical AI.

The orchestration platform that runs critical infrastructure on time.

Layrd is building a physician's favorite operating system.

Resurfacing your saved content.

Operating brain for modern manufacturing.

Data infrastructure for business teams.

Programmable RNA for cell modulation.

Developing RNA medicines to treat, delay, and prevent diseases of the brain.

Infrastructure for self-improving agents.

Building the AI expert for factories.

The orchestration layer for AI-powered risk management.

AI-driven analytics for mobile apps.

Autonomous bug-fixing development assistant.

AI agents that fully automate cybersecurity incident response.

The routing infrastructure for private aviation.

Jetpacks for life-extension of satellites.

Targeted data generation for AI developers.

AI to prevent post-surgical complications.

Brand brain for agentic marketing.

Autonomous underwater robots for marine work.

Giving domain experts the power to build, maintain, and scale their own automations.

The AI engine for the chemical industry.

Vanta for the consumer goods industry.

Supervised autonomy for construction vehicles.

Building powerful tools for food processing excellence.

Setting a new time standard for real estate development.

AI agents for IT teams.

AI agents for clinical trial management.

AI-powered network discovery that turns every connection into opportunities.

Modernizing legacy software.

Programmable yield infra for onchain liquidity.

Autonomous operations for industrial distributors.

Personal assistants at an affordable price.

The platform powering the next generation of insurance agencies.

AI-driven engineering for aircraft operations.

Helping companies deploy agents that undertake long-running tasks.

Subscription leasing for e-commerce merchants.

AI agents for customer operations.

Pixar lamp irl.

Developing conversational AI agents to transform job hunting and hiring.

Scaling video post-production.

AI credit-servicing platform to recover small balances.

Building the AI workforce for dental clinics.

An agent for making Roblox games with AI.

Making the web agent native.

The world's last property manager.

Advanced materials design & manufacture.

Cursor for creators.

AI-powered cardiac diagnostics.

Uncertainty-aware, explainable AI for critical mineral exploration.

Shopify for AI-built businesses.

Video editing agent with taste.

The revenue engineering layer for finance.

Security layer for Voice AI agents.

AI agents for strategic intelligence in pharma.

AI for finance and strategy.

Voice AI for inbound sales conversion.

AI agents for electronic component distribution.

Powering the internet economy for AI.

Photonic processing chips for embodied AI.

The financial infrastructure layer for modern energy and power.

AI infrastructure for complex litigation, starting with mass torts.

Autonomous on-call engineer.

AI agents for short-term rental management.

First AI-powered media infrastructure platform for e-commerce merchants.

The data and compute infrastructure that moves biology from wet lab to GPU cluster.

First Voice AI OS for agriculture.

AI compression algorithms for Earth Observation satellites.

AI companion for personal productivity.

The first autonomous insurance broker.

Software and hardware to secure and verify large AI clusters.

Ambient AI for surgery to automate operative reports and billing.

Unlocking the power of AI, for regulated industries.

World's best AI.

Your autonomous pre-construction team. Starting with estimates.

AI-guided materials synthesis for industrial manufacturers.

Influencer-partnership automation for marketing teams.

Photonic computing platform to unlock AGI at scale.

Government contracting automation for small businesses.

Regulatory compliance for digital health teams.

The modern workforce solution for UK healthcare.

Runtime supervision for AI agents.

AI-generated UX patterns for conversion optimization.

AI copilot for audio production.

ML-driven covalent inhibitors for oncology teams.

Building the foundational capability for developmental intelligence.

The construction intelligence layer.

AI-native bookkeeping automation for accountants.

AI for the built world.

A new kind of AI and compute company: accelerating the coevolution of intelligence and chips.

AR design assistant for interiors and renovations.

AI paralegal for corporate legal teams.

The AI engine powering real-time medical necessity decisions.

AI code review for faster, secure pull requests.

Computer vision for construction progress tracking.