Entrepreneur First companies
The Entrepreneur First portfolio as the radar sees it: synced daily, classified into clusters, checked for life and movement. 523 companies.
clusterVertical AI agents 47Healthcare and bio 16Robotics and physical world 12Fintech 11Developer tools 10AI infra and compute 8Horizontal AI assistants 7Agent infrastructure 6B2B SaaS 6Consumer 6Security and compliance 5Data for AI 5Climate and energy 4Commerce and marketplaces 4Defense and space 4Other 2
| Company | Cluster | Program | Status | Last signal |
|---|---|---|---|---|
| Sekkari Photonic processing chips for embodied AI. | AI infra and computePhotonic processing chips for inference | Entrepreneur FirstEF London 2025 | Active | checked 2026-08-23 |
| Tacit MachinesAI The data and compute infrastructure that moves biology from wet lab to GPU cluster. | AI infra and computeBiocompute infrastructure | Entrepreneur FirstEF London 2025 | Active | checked 2026-08-23 |
| Ulyssean Software and hardware to secure and verify large AI clusters. | AI infra and computeAI cluster resilience chips | Entrepreneur FirstEF London 2025 | Active | checked 2026-08-23 |
| WisentAI World's best AI. | AI infra and computeFoundation models and inference | Entrepreneur FirstEF London 2025 | Active | checked 2026-08-23 |
| AragoAI Photonic computing platform to unlock AGI at scale. | AI infra and computePhotonic AI accelerator chip | Entrepreneur FirstEF Paris 2024 | Active16 open roles | checked 2026-08-23 |
| CallosumAI A new kind of AI and compute company: accelerating the coevolution of intelligence and chips. | AI infra and computeAI workload orchestration platform | Entrepreneur FirstEF London 2024 | Active20 open roles | checked 2026-08-23 |
| Peripheral LabsAI Spatial AI for live sports and media production. | AI infra and computeNeural rendering for live sports | Entrepreneur FirstEF San Francisco 2024 | Active | checked 2026-08-23 |
| ZeroEntropyAI AI retrieval for AI agents and RAG applications. | AI infra and computeSpecialized retrieval models | Entrepreneur FirstEF San Francisco 2024 | Acquired | checked 2026-08-23 |