NEXI Biotech Inc

What it does

NEXI Biotech Inc is an innovative lifetech company focused on advancing neurological drug discovery through in vitro neurotechnology models. By engineering human iPSC-derived brain circuits on high-density microelectrode arrays, NEXI generates high-resolution, spatiotemporal electrophysiological data at single-cell resolution. This approach addresses the limitations of traditional animal models and static organoids, which often yield misleading efficacy signals contributing to high clinical failure rates in CNS drug development. NEXI’s platform measures emergent circuit dynamics within a canonical cortical-striatal-thalamic architecture, applicable to a broad range of neurodegenerative, neurodevelopmental, and neuropsychiatric diseases. The technology has supported multiple investigational new drug applications by providing human cell-based efficacy data, enhancing translational predictability. Offering a flexible business model that includes fee-for-service and licensing arrangements, NEXI Biotech provides scalable solutions to reduce risk and improve outcomes in CNS therapeutic development, representing a significant innovation in neuropharmacology and drug validation.