cluster
Agent infrastructure startups
Infrastructure FOR AI agents: orchestration, memory, evals, identity, agent payments, browser automation, self-maintaining APIs, MCP tooling.
460
companies tracked
221
from the last 2 years
33
startup-relevant federal grants ($13M)
Share of accelerator intake by year
Newest in the cluster
- herdrY Combinator F26
building the open agent runtime
- SimanticY Combinator F26
Firmware simulation for AI agents
- antimattrY Combinator F26
voice-first hardware interface for human-agent interaction
- AmuletY Combinator S26
High performance file system for agents
- SpaceFlow Technologies, Inc.Y Combinator S26
The managed runtime for enterprise AI agents
- 6thSenseY Combinator S26
A nervous system for physical AI
- Ooak DataY Combinator S26
We turn company data into RL environnements.
- DaqstraY Combinator S26
AI-native orchestration for physical R&D testing
- Financial DatasetsY Combinator S26
Connect your agent to the stock market
- ExecutorY Combinator S26
The open source integration management layer for AI.
- InkboxY Combinator S26
Let your agents communicate via email, phone, iMessage, & Agent2Agent
- Agnost AIY Combinator S26
Product analytics for AI Agents
Most AI-visible
Highest AEO scores - how well AI assistants can read and cite them.
- Nexus70
- Confident AI70
- Kaelio70
- Hamming AI69
- Chamber69
- Blaxel68
- Jinba67
- Mem067
By program
- Y Combinator350
- Plug and Play45
- Techstars39
- a16z speedrun12
- 500 Global12
- SOSV2
Browse all 460 Agent infrastructure companies →
Updated hourly from accelerator directories, funding news and federal grant data.